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The Chinese herbal medicine formula MSSM-002 suppresses allergic airway hyperreactivity and modulates TH1/TH2 responses in a murine model of allergic asthma
Xiu-Min Li MDaa, Chih-Kang Huang MSaa, Teng-Fei Zhang PhDaa, Ariel A. Teper MDaa, Kamal Srivastava BSaa, Brian H. Schofield JDba and Hugh A. Sampson MDaa
aFrom the aDepartment of Pediatrics, Mt Sinai School of Medicine, New York, NY, and the bDepartment of Environmental Health Sciences, Johns Hopkins University School of Hygiene and Public Health, Baltimore, Md.
Background: Asthma is a major public health problem worldwide, and the morbidity and mortality of asthma have increased in the past two decades. The reputed efficacy, low cost, and relative absence of side effects of traditional Chinese medicines (TCMs) have led to increasing interest in the use of TCMs for the treatment of asthma in Western countries. However, there are few well-controlled scientific studies on the efficacy, safety, and mechanisms of action of TCMs used to treat asthma. Objective: The goal of this study was to investigate the effects of the Chinese herbal medicine formula MSSM-002, derived from TCMs used to treat allergic asthma, on a well-characterized mouse model of allergic asthma. Methods: Mice sensitized intraperitoneally and challenged intratracheally with conalbumin were treated with MSSM-002 24 hours after the first intratracheal challenge.
Study on Pharmacological Effect of Bi yan Pian
Pharmacology and Clinics of Chinese Materia Medica 2000
Studies on pharmacodynamics of the Tablet Cang'e Bi yan Pian
Pharmacology and Clinics of Chinese Materia Medica 2004
Preparation and observation of clinical effect of Tongqiao Bi yan pellets
Northwest Pharmaceutical Journal 2007
Identifieation Distinguishing of Ditong Bi yan Liquid by TLC
Journal of Modern Food and Pharmaceuticals 2007 Determination of Baicalin in Xinfang Bi yan Capsules by HPLC
Chen Feng-lei Li Bao-guo
Qilu Pharmaceutical Affairs 2005
Determination of imperatorin in Tongqiao Biyan capsules by HPLC
West China Journal of Pharmaceutical Sciences 2003
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